routes added to the routing table using the "route" command are purged when the computer is rebooted. However, if you use it with the “-p” parameter, you can make a route persistent. The route will not be deleted from the routing table upon restart.

route add -p [network address] mask [subnet mask] [gateway] metric [value]
eg:

route add -p 140.4.8.0 mask 255.255.255.0 140.1.1.242